LAFIRE - a new automated refinement program for macromolecular crystallography. I saw it in the new Acta. Cryst. D:

Acta Cryst. (2006). D62, 189-196 [ doi:10.1107/S0907444905038965 ]
LAFIRE: software for automating the refinement process of protein-structure analysis
M. Yao, Y. Zhou and I. Tanaka

Synopsis: A manual intervention-free automatic refinement software package (LAFIRE) has been developed for high-throughput protein-structure analysis. This program begins from an initial model that can be approximate, fragmentary or even only main-chain and performs a whole refinement process to provide a final model including water molecules.