Friday, February 25, 2005


Position dependence of non-polar amino acid intrinsic helical propensities1

Michael Petukhov, 1, Victor Muñoz1, Noboru Yumoto2, Susumu Yoshikawa2 and Luis Serrano1

We have interpreted the results from these experiments with the model of the helix/coil transition (AGADIR), that indicates that the intrinsic helical propensity is position dependent. Gly, Val and Ile are more favorable at the first turn than in the middle of the -helix, while for Leu and Met we observe the opposite behavior.